R03 awarded to develop tools for controlling rotator cuff muscle activation using light

The Killian Lab recently received funding from the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) to develop in vivo optogenetics tools for the control of skeletal muscle contraction. We will use these tools to identify the role that increased muscle loading plays on enthesis maturation during postnatal … Continue reading R03 awarded to develop tools for controlling rotator cuff muscle activation using light

Art in Science

This year's Art in Science features work from the Killian lab, submitted by our graduate student, Ryan Locke! Join us on Opening Night at Blue Ball Barn in Wilmington, DE where the artwork will be on display from May 4th through June 1st. Opening Night will be on Friday, May 4th from 5:30PM – 8:30PM for the Art in Science Meet the Artist Event. This is … Continue reading Art in Science

Recent publications from LIMBR

Check out our recent publication in JBME, led by PhD student, Ryan Locke! In collaboration with the Elliott Lab at UD, we aimed to experimentally track the tissue-scale strains of the tendon–bone attachment with and without a localized defect. Regardless of the attachments’ ability to reduce localized stress, rotator cuff tendon injuries are common and occur predominantly near the … Continue reading Recent publications from LIMBR

Summer Blog Series from the Killian Lab

Welcome to our first-ever summer writing project! I am excited to share a few snippets from the different voices of our lab. What to expect: We'll be featuring student-authored blog posts from graduate students, undergraduate scholars, and high school researchers. These posts will range from "how-to" checklists, to interviews with some of our lab members, as well as perspectives on personal experiences related to research and professional development. Target audience: Anyone who wants to learn more about life and interests of the individuals working in an academic lab, particularly one that is integrative across multiple disciplines. When to expect the posts: We'll roll out the posts throughout the summer and into fall, so check back in to our website often for some fresh perspectives.

Beth Lemmon receives DE INBRE Summer Scholars Fellowship

Congratulations to Beth Lemmon, a rising senior in our group, on receiving one of the prestigious spots as a 2017 Delaware INBRE Summer Scholar! Beth will spend this summer continuing work on her independent project studying the healing response of partial width tendon-bone defects in the rat rotator cuff.

New review published in ACS Biomaterials Science and Engineering

Ryan Locke (1st year PhD student in Dr. Killian's lab) and Professor Killian co-authored a review, published in ACS Biomaterials Science and Engineering, on the multiscale, morphological, and mechanical characteristics of the fibrocartilage attachment. This review discusses historical and recent clinical approaches to treating enthesis injury and explores new technological advancements in tissue-engineered biomaterials that have shown promise … Continue reading New review published in ACS Biomaterials Science and Engineering

Professor Killian receives IREK12 Career Development Award

Dr Killian has been selected as a scholar for the Interdisciplinary Rehabilitation Engineering Career Development Program (IREK12) in Movement and Rehabilitation Sciences, which operates out of Northwestern University. Killian’s research will focus on rotator cuff tears, a common orthopedic problem that leads to shoulder pain, dysfunction and degeneration. More info can be found here: http://www.udel.edu/udaily/2016/november/rotator-cuff/

New paper from Killianlab: Role of Scleraxis in fracture healing

Recently published work from the Killian Lab describes the role of Scleraxis in the formation of a symmetric callus following long bone fracture. The paper, titled: "Loss of scleraxis in mice leads to geometric and structural changes in cortical bone, as well as asymmetry in fracture healing," was accepted for publication in The FASEB Journal. Authors … Continue reading New paper from Killianlab: Role of Scleraxis in fracture healing

Recent funding award from UDRF

Dr. Killian recently received funding from the University of Delaware Research Foundation to identify the role of chondrogenesis, driven by fibroblast growth factor 18, in tendon-to-bone attachment maturation and healing. This research will support graduate level work in basic and translational musculoskeletal research.