Performing A Literature Review And Managing References

About the Author: Seth is a rising senior undergraduate in Biomedical Engineering at the University of Delaware. He participates in volunteer microbiology research and has been involved in the Killian Lab since 2016. He is an Undergraduate Research Fellow and is currently developing a tissue engineering tendon platform to study the enthesis. An important part of … Continue reading Performing A Literature Review And Managing References

New review published in ACS Biomaterials Science and Engineering

Ryan Locke (1st year PhD student in Dr. Killian's lab) and Professor Killian co-authored a review, published in ACS Biomaterials Science and Engineering, on the multiscale, morphological, and mechanical characteristics of the fibrocartilage attachment. This review discusses historical and recent clinical approaches to treating enthesis injury and explores new technological advancements in tissue-engineered biomaterials that have shown promise … Continue reading New review published in ACS Biomaterials Science and Engineering

New paper from Killianlab: Role of Scleraxis in fracture healing

Recently published work from the Killian Lab describes the role of Scleraxis in the formation of a symmetric callus following long bone fracture. The paper, titled: "Loss of scleraxis in mice leads to geometric and structural changes in cortical bone, as well as asymmetry in fracture healing," was accepted for publication in The FASEB Journal. Authors … Continue reading New paper from Killianlab: Role of Scleraxis in fracture healing

New paper published in the Journal of Orthopaedic Research

New work from the Killian Lab, in collaboration with Washington University and Imperial College London, on hip muscle imbalance during postnatal growth was recently accepted for publication in the Journal of Orthopaedic Research. Abstract: The mechanical loading environment influences the development and maturation of joints. In this study, the influence of imbalanced muscular loading on joint … Continue reading New paper published in the Journal of Orthopaedic Research

New paper published in FASEBJ on the role of Scleraxis in tendon enthesis maturation

Check out our most recent paper, Scleraxis is required for the development of a functional tendon enthesis (Killian Thomopoulos FASEBJ 2015), which was just published in the FASEB Journal. This work identified Scleraxis as an important contributor to enthesis maturation by showing that loss of Scleraxis leads to impaired biomechanical function of the tendon-to-bone attachment and also leads to … Continue reading New paper published in FASEBJ on the role of Scleraxis in tendon enthesis maturation

New paper published in AJSM

Dr. Killian and collaborators recently published a paper titled: "Chronic Degeneration Leads to Poor Healing of Repaired Massive Rotator Cuff Tears in Rats," in the American Journal of Sports Medicine. Chronic, degenerative rotator cuff tears are difficult to repair, and "successful" repairs tend to fail after surgery. This is a problem, in particular, for patients over the … Continue reading New paper published in AJSM