The Killian Lab recently received funding from the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) to develop in vivo optogenetics tools for the control of skeletal muscle contraction. We will use these tools to identify the role that increased muscle loading plays on enthesis maturation during postnatal … Continue reading R03 awarded to develop tools for controlling rotator cuff muscle activation using light
Congratulations to Beth Lemmon, a rising senior in our group, on receiving one of the prestigious spots as a 2017 Delaware INBRE Summer Scholar! Beth will spend this summer continuing work on her independent project studying the healing response of partial width tendon-bone defects in the rat rotator cuff.
Beth Lemmon (CANR undergraduate) received the 2016-2017 Undergraduate Tuition Award from the Delaware Space Grant Consortium, supported by the National Aeronautics and Space Administration (NASA) National Space Grant College and Fellowship Program. Ms. Lemmon will continue her research efforts in the killianlab this fall. Congratulations, Beth!
Check out our most recent paper, Scleraxis is required for the development of a functional tendon enthesis (Killian Thomopoulos FASEBJ 2015), which was just published in the FASEB Journal. This work identified Scleraxis as an important contributor to enthesis maturation by showing that loss of Scleraxis leads to impaired biomechanical function of the tendon-to-bone attachment and also leads to … Continue reading New paper published in FASEBJ on the role of Scleraxis in tendon enthesis maturation
Dr. Killian and collaborators recently published a paper titled: "Chronic Degeneration Leads to Poor Healing of Repaired Massive Rotator Cuff Tears in Rats," in the American Journal of Sports Medicine. Chronic, degenerative rotator cuff tears are difficult to repair, and "successful" repairs tend to fail after surgery. This is a problem, in particular, for patients over the … Continue reading New paper published in AJSM